Buryak M. Development of technology of dense oak bark extract and creation of ointment on its basis.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U005127

Applicant for

Specialization

  • 15.00.01 - Технологія ліків, організація фармацевтичної справи та судова фармація

05-06-2012

Specialized Academic Board

Д 64.605.02

National University of Pharmacy

Essay

Dissertation is devoted to development of the technology of new natural substance - thick extract of oak bark and to the grounding of composition and technology of the ointment on its basis. Based on the complex researches technology of extract is grounded, its physical and chemical properties are investigated, the methods of quality analysis are offered, a term of storage is determined. With pharmacological researches expressed anti-inflammatory and membranostabilising actions are set. Theoretically and experimentally the choice of emulsion base is grounded, structural-mechanical properties of the developed base are studied. With pharmacological and microbiological researches the optimal concentrations of extract – 3 % and essential oil of coriander – 0,5 % are set. Based on the conducted researches composition and technology of the ointment with extract and essential oil of coriander are developed.

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