Petizina O. The structural changes in the lymph nodes of rats at the influence of imunofan and cyclophosphanum

Thesis is devoted to the study of features of morphological changes in the structure of axillaries lymph nodes of immature and mature rats at the influence of imunofan and cyclophosphanum and correction of immunosuppression status by imunofan. Materials of thesis research complement the picture of the axillaries lymph nodes of the intact white outbred rats' males. First determined the influence of the imunofan and cyclophosphamide on the organometric and morphometric indexes of the lymph nodes rats' and structural features of the lymph nodes after correction of immune status by imunofan. The number of cell nucleuses per unit area of the lymph nodes in the all zones of lymph nodes after appointment of imunofan, cyclophosphamide and correction imunofan cyclophosphamide-induced changes was first studied. There were peculiarities of ultramicroscopic structure of lymph nodes of mature rats after imunofan administration and correction of immunosuppression status by imunofan. The correlation analysis of morphometric parameters in all groups' animals was done.