Demchenko T. Peculiarities of restoration of voluntary muscular movemets of flexors and extensors after damage of peripheral nerves of rats’ hind limbs.

It was found influence of unilateral sciatic nerve injury on the voluntary muscle contraction force of the distal hindlimbs (injured and contralateral) in rats. Functional reinner-vation of the flexors was characterized by a relatively greater initial force of contraction and more rapid recovery than those of the extensors. After injury of nerve the single and systemic injections of sodium gammahydroxybutyrate (NaGHB) have selective action against the injured structure. Shown that systemic injection of NaGHB within 4 weeks after injury the recovery of the muscle activity was accelerated on the side of compression of the nerve; the rates of such recovery in various muscles were dissimilar. Within the late time intervals (10th and 12th weeks) contractile force of the injured foot increased.