Zakon K. Differential approach of hemodialysis or hemofiltration usage in treatment of cardiac surgery patients with acute kidney injury

This study was dedicated to evaluate efficiency and indications for differential approach of different renal replacement therapy (RRT) modalities usage in treatment of cardiac surgery patients with acute kidney injury.Differential approach of different RRT modalities usage reduces hospital mortality of cardiac surgery patients with AKI. Continuous veno-venous hemofiltration (CVVH) reduces hospital mortality of cardiac surgery patients with oliguric, non-oliguric AKI and with AKI as a component of multiorgan failure (MOF) in comparison with predicted mortality by APACHE II scoring system, but hemodialysis reduces hospital mortality patients with AKI and without MOF. Continuous RRT modalities (CRRT) cause statistical significant reduction of hospital mortality of cardiac surgery patients with AKI as a component of MOF in comparison with intermittent RRT. CKD-III causes significant augmentation of hospital death risk in cardiac surgery patients with AKI by 3,5 times and by 8,1 times in cardiac surgery patients with AKI as a component of MOF.