Chaikovska M. Disorders of mineral, lipid metabolism and nutritional status of patients with chronic kidney disease

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U101422

Applicant for

Specialization

  • 14.01.37 - Нефрологія

20-04-2021

Specialized Academic Board

Д 26.565.01

State Institution "Institute of Nephrology NAMS of Ukraine"

Essay

The dissertation investigated the role of the c-terminal fragment of fibroblast growth factor 23 in the diagnosis of mineral and bone disorders, systemic inflammation, dyslipidemia and nutritional status decline of patients with chronic kidney disease. The effectiveness of combination therapy with levocarnitine and amino acids and their keto analogues was proven, which has a positive impact on general weakness and fatigue, proteinuria, reduces chronic inflammation, contributes to increase in the level of albuminemia and thickness of skin and fat fold, normalization of dyslipoproteinemia, accompanied by a decrease in the level of fibroblast growth factor 23 (p < 0,05).

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