Karpovskyi V. The role of higher nervous activity types in the regulation of lipid metabolism in pigs

The thesis is devoted to the studying of the nature and degree of influence of typological features of the nervous system on lipid metabolism in body of pigs of different age groups. For the first time established a close relationship between lipid metabolism in pigs of different age groups with indicators of nervous processes in cerebral cortex. Established the functional connection of strength, balance and mobility of cortical processes with parameters of lipid metabolism in the body of pigs, and the degree of influence of individual features of nervous system on parameters of lipid metabolism in the body of pigs after weaning from sows. In the thesis was disclosed the degree of influence of typological characteristics of higher nervous activity on the dynamics of triacylglycerols and total cholesterol content, as evidenced by high functional connection of strength, balance and mobility of cortical processes with these indicators. In particular, it was found that the content of triacylglycerol and total cholesterol in blood serum of piglets before weaning significantly depends on the strength of cortical processes in animals (n^2х=0.48–0.73; p<0.05–0.001), and inversely correlates with the main characteristics of cortical processes (r=-0.64–0.90 (p<0.01). After weaning is reduction of triacylglycerols (by 1.5–2 times) and total cholesterol (by 12–50 %) in blood serum of pigs. Decreasing of cholesterol is due to low-density lipoprotein cholesterol (by 2.1–2.8 times; p <0.001). The features of the fatty acid composition of blood serum in animals of different types of higher nervous activity were studied. The decrease of monounsaturated fatty acids content in blood serum of sows of weak type of higher nervous activity by 11–14 % (p<0.05) is due to reduction of myristoleic fatty acid content. Shown a higher intensity of trans fatty acids metabolism in the body 3-year sow of strong balanced inert type of higher nervous activity (by 29–35 %) and lower – in animals of strong unbalanced and weak types (by 1.4–1.6 times) in compare with animals of strong, balanced and mobile type of higher nervous activity.