Skrypkina V. The autonomic nervous regulation of antioxidant system in organism of sows

The thesis is devoted to studying the nature of the interaction of autonomic regulation mechanisms of antioxidant defense system and the intensity of lipid peroxidation in the body of pigs. For the first time found the close relationship between the tone of autonomic nervous system and intensity of lipid peroxidation in blood of pigs. It is scientifically proved the differences in level of production and inactivation of lipid peroxidation products in animals of different tone of autonomic nervous system. Established that with the increase of the tone of the autonomic nervous system in pig vagotonics is reduction of hydroperoxides lipids content (r=-0.99; p<0.001). Convincing conclusions were made about the direct functional relations between diene conjugates content in blood plasma of animals sympathicotonics and vagotonics (r=0.71 and r=0.81; p<0.05) and tone of autonomic nervous system. In the thesis disclosed the relationship of tone of autonomic nervous system with activity of antioxidant defense system in blood of pigs. In particular, the activity of antioxidant enzymes in blood of animal sympathicotonics is at significantly higher level than such in animals normotonics and vagotonics. Established shift in the balance of antioxidant defense system in animals sympathicotonics towards activity its enzymatic level. Investigated the features of Copper, Zinc, Iron and Magnesium content in blood plasma of animals of different tone of the autonomic nervous system and established close functional relationships and reliable strength of impact the tone of autonomic nervous system on content of these metals in blood of pigs.