Iroko E. Development of composition and technology of dental gel based on raw materials of natural origin

The thesis is devoted to developing new pharmaceutical gel based on dense oak bark extract and dry extract of aloe for use in dentistry for the treatment of inflammatory periodontal disease and oral mucosa. Based on comprehensive research technology of gel "Aloe-Dental" was substantiated. Using modern research methods of identify and of quantitative determination the active components of the gel were developed. Osmotic properties of the gel and the extent of the release of active substances from it were studied and the results of studies specific activity and safety of the developed gel were summarized. Stability of the developed "Aloe-dental" gel is proved during two years at a temperature not higher 25 ° С. Proposed project quality control methods and technology of "Aloe-dental" gel has been tested under industrial conditions. Pharmacological studies have expressed parodonto-protective, reparative, anti-microbial and anti-inflammatory action.