Kharchenko-Sevriukova G. Specifics of pathological processes in oral cavity in patients with chronic obstructive pulmonary disease

Object of study: chronic obstructive pulmonary disease in patients with pathological processes of the oral cavity; the goal: to improve the diagnostics of pathological processes of the oral cavity in chronic obstructive pulmonary disease (COPD) patients by means of study of clinical COPD symptoms, pathologic processes of periodontal tissue, condition of the local immunity of the oral cavity and immunologic markers of systemic inflammation, indicators of systemic osteoporosis and study of densitometry indicators of the sponge alveolar bone tissue density; methods of Investigation: questionnaire, general clinical and periodontal examination, biochemical and immunological research methods, external respiration functional test, X-ray, statistical methods; novelty: for the first time, the structure and the clinical peculiarities of pathologic processes of the oral cavity in COPD patients were studied; scientific data on specific conditions of the local immunity of the oral cavity and the systemic inflammation markers in COPD patients with pathologic processes of the oral cavity were updated; it was established that 98.4 % of COPD patients show systemic disorders of the mineral metabolism manifested through considerable decrease of mineral density of the skeletal system, while being clinically diagnosed as osteopenia in 28.6 % of patients and in 69.8 % of patients - as osteoporosis; peculiarities of the densitometry indicators of the sponge alveolar bone tissue and the maxillary tuber density were determined; it has been proven that the risk of development of osteoporosis of the alveolar bone tissue and the maxillary tuber in COPD patients increases depending on the duration of the main disease, smoking experience, and progression of bronchial obstruction. Field of application - medicine.