Symonik A. The role of oxidative-nitrative stress in the process of adaptation to physical loads

It was proved that the improvement of the whole functional state of trained persons in the process of systematic implementation of physical activity was carried out by the way of activation of enzymatic and non-enzymatic mechanisms of oxygen active forms generation, optimization of the synthesis of nitric oxide, as well as maintaining optimal activity of lipid peroxide oxidation. The high correlation dependence that persisted during the whole research for all surveyed individuals, regardless of gender and form of adaptation to physical activity was established between the integral indicator of the functional state, maximum oxygen consumption and the indices of energy supply system, cardiovascular system, external breathing system, manifestation of oxidative-nitrative stress and intensity of lipid peroxide oxidation. The results of the research reveal the possible physiological mechanism of oxidative-nitrative stress influence on the process of adaptation to regular physical activity.