Dolynko N. Morphofunctional state of the testis and prostate in norm, under the influence of ethanol intoxication and its correction

The dissertation is devoted to the establishment of the morphofunctional organization of the bloodstream and tissue components of the testicle and prostate gland in norm, their rehabilitation under the condition of chronic ethanol intoxication and correction of spermatogenesis in the experiment. It has been established that prolonged alcoholization of animals leads to focal deformation of the blood vessels of the hemomycocirculatory canine of the testicles, focal atrophy of the parenchyma with a decrease in the concentration of sperm in the ejaculate, the number of living and morphologically normal sperm, and an increase in their pathological forms, including fragmentated DNA. There are significant ultrastructural changes in the components of GTB and parenchyma of the prostate gland. In the long term, the elimination of ethanol in the testicles and prostate gland of the expressed recovery processes is not observed. Prolonged application of phytopreparations of the extract of Ginkgo biloba leaves in alcoholated animals is accompanied by a decrease in the number of convoluted seminal tubules with an affected spermatogenic epithelium, an increase in the concentration of sperm in the ejaculate, the number of living and normal sperm with progressive motion. The depth of damage to structures of GTP, DNA of sperm and glandular epithelium of the prostate gland decreases.