Zinko G. Therapeutic and prophylactic effect of Selenium and Germanium compaunds in calves with abomazoenteritis

Object of research - abdomazoenteritis in calves. The purpose of research - experimentally and theoretically the therapeutic and prophylactic efficacy of Sel-Plex and Maxidin 0.4 preparations with immunomodulating and antioxidant effect and their effect on the state of lipid peroxidation, endogenous intoxication, antioxidant and immune defense in healthy and calves with abdomenogenital calves. Methods of investigation - clinical, morphological, physical, biochemical, immunological, bacteriological, pathologic-anatomical, pathological-morphological, statistical. Scientific novelty: for the first time, data characterizing the intensity of lipid peroxidation processes and the state of endogenous intoxication, antioxidant defense systems, cellular and humoral immunity in calves with abomazoenteritis with preparations Sel-Plex and Maksidin 0.4 in combination with an antimicrobial (Amoxycillin 15% LA), replacing (trivitamin) and rehydration therapy. The connection and role of the immune and antioxidant systems was studied, which made it possible to disclose individual links of the pathogenesis of abomazoenteritis in calves. The effectiveness of Sel-Plex and Maxidin 0.4 for the prevention of abomasoenteritis in calves is theoretically and experimentally proved for the first time. Their positive influence on the processes of lipid peroxidation, endogenous intoxication, the state of the antioxidant system, cellular and humoral immunity was investigated. Implemented: the obtained results are used in scientific research and teaching work at the faculties of higher educational institutions of the III-IV accreditation levels. Sphere (industry) of use: veterinary medicine