Furda I. Epizootological control of porcine reproductive and respiratory syndrome and porcine circovirus infection in Ukraine

The dissertation presents new data on the scientific substantiation and improvement of the system of epizootological control of porcine reproductive and respiratory syndrome and porcine circovirus infection, which includes: serological monitoring; study of molecular genetic characteristics of isolates of pathogens; estimation of epizootic manifestation with definition of directions of infections spread; development of modeling and forecasting system; analysis of the epizootic situation with the involved prevention, struggle and eradication measures of porcine reproductive and respiratory syndrome and porcine circovirus infection. Based on conducted serological monitoring of porcine reproductive and respiratory syndrome and porcine circovirus infection in the pig farms of Ukraine for the period 2013–2017 has established a seroprevalence of porcine reproductive and respiratory syndrome (24.52 %) and porcine circovirus type 2 (68.62 %). Based on the results of a full-genome sequencing of porcine circovirus type 2 isolates and analysis of nucleotide sequences, we confirmed the persistence of porcine circovirus type 2 in domestic pigs in Ukraine. Were constructed own model of epizootic manifestation of porcine reproductive and respiratory syndrome and porcine circovirus infection. Was proposed a rational way to determining the correlation coefficient and its reliability to find out the connection between porcine reproductive and respiratory syndrome and porcine circovirus infection. The medium-term prognosis of porcine reproductive and respiratory syndrome and porcine circovirus infection up to 2022 was provides: tendency to increase seroprevalence of porcine reproductive and respiratory syndrome (will be about 60 % in early 2019 and will increase in the future) and 97–100 % of the seroprevalence of porcine circovirus infection over the entire forecast period (2018–2022). The porcine circovirus type 2 virus will spread more rapidly than the virus of porcine reproductive and respiratory syndrome by 2,39 times under the same conditions.