Tsytovskyi M. The morphological characteristics of the hemomycocirculatory channel of the laboratory rodent aortic wall in normal catastasis and in experimental diabetes catastasis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0419U004315

Applicant for

Specialization

  • 14.03.01 - Нормальна анатомія

23-09-2019

Specialized Academic Board

К 76.600.01

HSEE of Ukraine "Bukovinian State Medical University"

Essay

The dissertation presents a theoretical generalization and a new solution to the scientific problem of establishing the features of the structure and blood supply of the aortic wall of a white rat. For the first time, histological and morphometric features of the thickness of the aorta wall, the thickness index of tunica media of the aorta wall, the thickness of the elastic occasional membrane of the tunica media of the aorta wall, the outer and internal diameter of the arterioles, the diameter of venules and capillaries of the rat were established.The dissertation presents a theoretical generalization and a new solution to the scientific problem of establishing the features of the structure and blood supply of the aortic wall of a white rat.The comparison of morphological and morphometric indices of the aortic wall structure and its hemomicrocirculatory bed in white rats under normal conditions and after 2, 4, 6, 8 weeks of experimental diabetes mellitus.To trace the dynamics of the microstructural and ultrastructural rate of the laboratory rodent aortic wall at the different times (at 2, 4, 6 and 8 weeks) in the course of the streptotsotocin-induced of experimental diabetes.The statistical method that has been held has allowed to arrange the experimental results and give the comparative analysis about angioarchitectonics of aortic wall of the white laboratory rodent in normal catastasis and in the course of the streptotsotocin-induced of experimental diabetes. The results of the study of the structural features of the aorta of white rat normal and experimental diabetes is fundamental and is of practical importance for morphologists, endocrinologists, cardiologists, vascular surgeons, as it can serve as a morphological basis for the development of new methods of diagnostics and treatment of pathology in patients with diabetes mellitus.

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