Sliesarenko Y. Etiological diagnosis and cure optimization of the viral and bacterial pneumonia in the military servants of joint troops, mobilized for antiterrorist military zone

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0420U100291

Applicant for

Specialization

  • 14.01.27 - Пульмонологія

13-01-2020

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

Object of research: community-acquired pneumonia (САP) resulting from an outbreak of acute respiratory viral infections (ARVI) in servicemen mobilized to serve in the area of a anti-terrorism operation / joint force operation (ATO/JFO); methods of research: clinical, radiological, bacteriological, virological, pharmacoeconomic and statistical; the novelty: morbidity of community-acquired pneumonia among mobilized for passing service in the ATO/JFO zone is closely related with ARVI outbreak; particularly detailed and scientifically based new approaches to the САP diagnostics based on the most up-to-date technology and identification of bacterial and external knowledge have been made, which allowed the use of these algorithms to be identified from monoplex and multiplex polymerase lanceous reactions in real time and express tests with immunochromatographic tests (IС-tests) in the training center as well as rapid IС-tests in the ATO/JFO zone; cause of ARVI outbreaks in mobilized for service in the ATO/JFO zone in the majority cases are adenovirus and rhinovirus; among the bacterial pathogens of CAP III clinical group in this contingent of patients the main are S. pneumoniae and S. aureus; ways of optimization of existing antimicrobial therapy regimens for patients with CAP clinical trial group III mobilized for service in the ATO/JFO zone are proposed, during their stay in the training center and during combat operations; on the basis of pharmacoeconomic analysis, the use of antibacterial drugs in combination with the antiviral agent is substantiated. Scope - medicine.

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