Savenko M. Optimization of surgical and conservative treatment of intussusception in children (experimental and clinical study)

Dissertation is devoted to improvement of surgical and non-surgical treatment of children with intussusception.In this scientific work, based on the analysis of the first group of patients: 572 cases and 70 case histories of children with intussusception who had operated by laparotomy. It decided to apply the method of laparoscopy in conjunction with intraintestinal pneumatic compression in cases where the usual conservative treatment is not effective (Patent No. 58202). In order to reduce the trauma of surgical treatment in cases where conservative reduction of intussusception is ineffective, laparoscopic reduction of intussusception with simultaneous air injection into the large intestine. The unsolved question is precisely the safety of the combination of the method of laparoscopy with pneumatic reduction of intussusception using. Searching for answers to this question in open literary sources had ambiguous and incomplete answers. The aim of experimental part of the research is modeling and studying the effect of increased intra-abdominal pressure depending on the pressure level and duration of exposure to parenchymal organs and target organs of the abdominal cavity and retroperitoneal space: liver, intestine, kidneys, adrenal glands. An experimental study was conducted on 48 (9 of them died during the experiment) nonlinear white rats-males in two series of the experiment: acute and chronic. The developed method of minimally invasive laparoscopic treatment of intestinal invagination allows improve the results of treatment. An experimentally determined limiting laparoscopic laparoscopy time in terms of intraocular pneumatic compression allows you to safely use a combination of these methods. Using the developed method will reduce the time of the patient in the hospital.