Yarema I. Development of emulgel composition and technology for the androgenic alopecia treatment

The dissertation is dedicated to the theoretical and experimental substantiation of structure and technology of medical cosmetic remedy (MCR) in the form of an emulgel with the Serenoa repens dry extract (SRDE) and Sophora japonica tincture (SJT), intended for use in trichology, namely for the prevention and treatment of androgenic alopecia (AA). On the basis of pharmacotechnological research the technological parameters of the emulgel production were defined, namely: temperature mode – 60 °С, emulsification with alternate introduction of oil and water phases to a mixture of emulsifiers, homogenization during 30 min at a speed of 2000 rpm. Taking into account the investigation results the emulgeloptimal technology in compounding pharmacy and industrial conditions was substantiated. The technology of the emulgel was described in the Information Letter «Technology of manufacturing a combined herbal preparation «Flavosterol-emulgel» for local treatment of androgenic alopecia in pharmacies» and was tested in pharmacies with extemporaneous drug compounding.