Lobanov I. Formation of mental and behavioral disorders due to use of alcohol of adolescents with perinatal pathology in anamnesis

The dissertation is devoted to a comprehensive study of mental and behavioral disorders due to alcohol consumption with onset in adolescence of persons with perinatal pathology in anamnesis to solve the problem of improving their prevention and development a comprehensive step-by-step method of achieving therapeutic remission in these disorders. The study includes 231 adolescents and 87 patients with clinical forms of AUD (F10.2, F10.3). The studied persons were divided into 6 groups. The selected groups were considered as a continuum of stages in the formation of the AD. To achieve the goal and objectives of the study, psychodiagnostic, psychometric, medico-sociological, clinical-anamnestic, biochemical, anthropometric and statistical methods were used. A high frequency of alcohol consumption by adolescents and a large percentage of persons who at the age of 15 – 19 have separate signs of AD were found. It was found that the pathological process of AUD formation proceeds against the background and with the participation of the consequences of brain lesions in the perinatal period. The most pathogenic complications of the perinatal period are drug induction of labor or surgical delivery, prolonged labor, trauma or serious illness during pregnancy and measures to maintain pregnancy. It was revealed that the formation of disorders due to alcohol consumption during puberty occurs against the background of an increase in T and F within the average normative level, is a risk factor for persons with a history of perinatal pathology, at the same time, the level of T content at the lower limit of the norm is inherent in abstainers and persons who occasionally consume alcohol. Prevention should begin at the pregravid stage, be interdepartmental and multi-professional. The method of treatment consists of monitoring the condition and response to treatment, psychoeducation, psychotherapy and pharmacotherapy. Based on the results of approbation, the high efficiency of the proposed treatment program was proved.