The purpose of the study was to develop and experimentally substantiate a methodology for building the training process of young 12-15-years-old female athletes engaged in kettlebell lifting, taking into account the formation and functioning of a specific biological cycle. Object of the research was the training process of young female athletes engaged in kettlebell lifting 12-15 years old. Complexes of methods were used as research methods: analysis and generalization of literature data, questionnaires, pedagogical observation of the training process of young female athletes engaged in kettlebell lifting 12-15 years old, pedagogical experiment, testing of physical qualities, biomedical methods with determining the functional state of the cardiovascular and respiratory systems, methods of mathematical statistics. In the course of the dissertation research, three groups of data were obtained: confirming, complementary or completely new. Confirmed data on the dependence of the formation of a specific biological cycle on the magnitude of physical activity and morphological and functional characteristics of young female athletes engaged in kettlebell lifting 12-15 years old that the female body in separate phases of the CMC equally reacts to various physical activities. The research results have been supplemented and expanded, the absence, when building the training process, of taking into account the CMC phases in young female athletes engaged in kettlebell lifting 12-15 years old slows down the formation and disrupts the cyclicity of a specific biological cycle. In the process of the conducted research, for the first time: complexes of exercises and a methodology for their use in basic mesocycles of annual training were developed, taking into account the formation of the musculoskeletal system and the formation of a specific biological cycle of young 12-15-years-old female athletes engaged in kettlebell lifting, the structure of the annual macrocycle of 12-15-year-old female athletes engaged in kettlebell lifting was substantiated, taking into account the phases ovarian-menstrual cycle; a correlation relationship was established between indicators of competitive and special exercises and morphological and functional indicators and indicators of general physical fitness, ensuring their implementation, female athletes engaged in kettlebell lifting 14-15 years old determined the factor structure of competitive activity under the influence of the use of exercise complexes developed for various muscle groups, selected for use in each phase of the CMC in basic mesocycles, which contains: the first factor (specialized strength) with a total contribution of variance – 41,2%, the second (functional) – 24,1%, the third (general physical fitness) – 19,2%, the fourth (anthropometric) – 8,7%, other factors make up - 6.8%; identified muscle groups that ensure the performance of competitive exercises in kettlebell lifting and developed a methodology for their development, taking into account the phases of a specific biological cycle.