Omelchenko N. Water-salt balance and reproductive function of the body of animals with long-term feeding of traditional and GM plant feeds

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U102800

Applicant for

Specialization

  • 03.00.13 - Фізіологія людини і тварин

11-05-2021

Specialized Academic Board

К 35.826.01

Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv

Essay

Object of research: physiological and biochemical processes in animal organism during long-term feeding of traditional and genetically modified soybeans. The purpose of the work: study of water-salt balance and animals reproductive function during long-term feeding by traditional and genetically modified plant foods (soybeans). Research methods: physiological (long-term changes observations of the state and body functions of experimental animals), physicochemical (studying of cations and anions in biological fluids), biochemical (indicators of total protein, creatinine, urea and enzyme activity), zootechnical (growth and development of animals, mass and mass indices of internal organs, milk productivity, preservation of offspring), statistical (processing of research results). Scientific novelty: For the first time, data on the long-term effects of heat-treated soybeans of traditional and transgenic varieties on the physiological condition and reproductive capacity of five generations female and male Wistar rats. It has been established that long-term feeding of heat-treated transgenic soybeans reduces the survival of offspring in suckling age, changes the kidneys of laboratory rats of both sexes functional state, accompanied by increased concentration and excretion of endogenous creatinine in urine, increased creatinine and creatinine. Feeding genetically modified soybeans does not cause significant changes in water-salt balance and does not affect the serum electrolytes of five generations rats. New data on the effect of argentum citrate solution obtained by nanotechnology on reproductive function, survival and development of offspring rats and cattle were obtained; functional state of rats excretory system; cows milk productivity against the background of long-term consumption of transgenic soybeans by animals as part of the feed ration. Suggested: To ensure high productivity and reproductive function, increase the preservation of offspring, agricultural enterprises are recommended to limit the feeding of genetically modified soybeans in the cows diets during lactation and to prefer the use in feeding by traditional soybeans. In order to reduce the negative impact of genetically modified soybeans on cows reproductive function and milk productivity, 1 μgAg / kg of animal body weight of argentum citrate obtained by nanotechnology should be fed during lactation. The results of the dissertation should be introduced into the educational process for students of agricultural and biological specialties of the university for teaching lectures on disciplines: animal physiology, animal feeding, reproductive biotechnology, milk production technology.

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