Kovalenko T. Cytogenetical and morphological oocytes characteristics associated with in vitro fertilization (clinics and experimental investigation)

Correlation between oocytes with normal morphology and Metaphase II stage, level of fertilization (both normal and abnormal) was estimated. The level of chromosome anomalies in oocytes of second meiotic metaphase comprised 53,0%. The decreasing of number and aggravation of morphological oocyte parameters correlates with decreasing of their fertilization rate. Decreasing of woman age influences on morphological and cytogenetics oocyte parameters in negative way. In groups of patients with different causes of infertility recovering oocytes distinguish by their morphological, functional parameters and fertilization potential. Results of age and different schemes of gormonal stimulation influence on unfertilized human oocyte parameters and oocytes from CBA mice where compared. 9 scientific papers within the context of disssertation had been published.