Bagrij D. Efficacy of progesterone in management of hypercapnia and respiratory acidosis in cor pulmonale patients

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U001786

Applicant for

Specialization

  • 14.01.27 - Пульмонологія

29-06-1999

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

The dissertation is dedicated to the management of hypercapnia and respiratory acidosis using progesterone in cor pulmonale patients. The positive effect of progesterone on blood gas composition and acid-base system develops 1week after initiation of therapy, achieving its maximum in 2 weeks. Then the stable level of physiological indices is usually observed. The pharmacodynamics of progesterone comprises stimulation of pulmonary ventilation - an increase of tidal volume, and reduction of respiration rate and deade spase.

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