Makar B. Forming and Topographo-Anatomical Correlations of the Nasal Walls with the adjacent Structures during Postnatal Human Ontogenesis.

220 specimens of the nasal portion of human corpses of different age periods, 80 roentgenograms and 30 computer tomograms. Objectives: a complex study of chronological regularities of morphogenesis and syntopic correlations of the nasal portion structures with the adjoining formations during the postnatal period of human ontogenesis. Methods of investigation and equipment: macroscopic, microscopic, common and fine anatomization, reconstruction, injection, roentgenographic, morphometric, statistical methods. Theoretical and practical value of the obtained findings: The results of the investigation may be used to estimate a developmental stage of the nasal region, especially in the early age, and to diagnose possible deviations from physiological development with the following surgical correction. The described peculiarities of deviations in the structure of the nasal-lacrimal duct, that may result in the development of dacryocystitis in newborns, are indicative of an obligatory participation of an otorhinolaryngologist in the liquidation of the given pathology. Topographic-anatomical peculiarities of the alipalatal node and nerve location in the posterior nasal walls should be considered in case of surgical manipulations on them. Morphological changes of the nasal walls in aged and old people are rather important to understand pathogenesis of possible complications from the adjoining organs, to choose a correct tactics of therapeutic and surgical treatment of various diseases in the nasal region of the above mentioned category of people. On the basis of morphological examinations we have introduced surgical method of treatment of cicatricial stenoses of the nasal-lacrimal duct. Scientific novelty of the obtained results : for the first time by means of adequate morphological methods a comprehensive investigation of structural and developmental peculiarities of the nasal wall topography and adjoining structures in the postnatal period of human ontogenesis has been conducted. The dynamics of changes of the shape and size of the nasal walls in different age periods has been observed. Topographic-anatomical interrelations of the nasal walls with the adjoining structures have been found and described, their morphological changes in the structure, variability, periods of intensive and slow development, peculiarities of syntopy of the vascular-nervous elements in different age periods have been determined. A separate stage of the nasal passages has been found that may be used in the completion of a new systematization of the development in the nasal walls pathology. The introduced surgical interventions in the nasal region and adjoining structures have been morphologically substantiated. The extent of introduction: The results of the investigation have been introduced into the teaching process of the Departments of Human Anatomy and Topographic Anatomy and Operative Surgery of medical higher schools and into the practice of ENT divisions of Ukraine's regional and municipal hospitals. Sphere of application : medicine,anatomy, surgery, otorhinolaryngology, ophthalmology.