Yablonska O. The immune stasis of deep-pregnant cows and newborn calves and its correction

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0505U000516

Applicant for

Specialization

  • 16.00.03 - Ветеринарна мікробіологія та вірусологія

19-10-2005

Specialized Academic Board

Д 26.004.03

National University of Life and Environmental Sciences of Ukraine

Essay

The stuffs about a becoming of an immunological homeostasis for the calves, his changes during of postnatal development, under influencing of a physiological condition animal, about outcomes of analysis of immunodeficiency condition and unknowns earlier aspects of this problem, about offered methods of correction and stimulation of an immune system in a complex of measures on preventive maintenance of gastrointestinal diseases of the calves are adduced. The researches have shown, that the immune system animal often appears be not capable to execute a function of preservation of a homeostasis, which one is subjected to authentic changes under influencing of changes of their physiological status, conditions of the contents, feeding and maintenance. The arising changes frequently receive nature of dysfunctional distresses, different species of immunodeficiency. Established, that pregnancy, specially it last third, is accompanied by a gentle dysfunction of a system of lymphocytes, depressing cell-like andmoderate depressing of humoral immunodefence, stimulation of helper's and dysfunction of a supressor's link of immunodefence. During of delivery and specially in the beginning of the puerperal term the immunodeficiency is aggravated, that it is possible to consider as a premorbidal condition of development of a puerperal pathology. The unsatisfactory conditions of maintenance and contents of the cows, their incomplete feeding promotes increase among the neonatal calves of number abortive and hypotrophic.By the conducted researches is established, that trecrezan, germatranol and saponit have corrective and challenging properties at immunodeficit condition animal. The scheme of an estimation of a nonspecific resistance and functional condition of an immune system for the cows is offered and calves with usage of the integral tests allows easily to troubleshoot a common condition of an immunological homeostasis animal, his changes during of illness, treatments and during convalescence and to receive the conformingmeasures.

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