Kotlyarenko L. Morphological patterns of small intestine structures remodelling depending on vegetative homeostasis of rats under death-cup (Amanita phalloides) poisoning

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0507U000283

Applicant for

Specialization

  • 14.03.01 - Нормальна анатомія

26-04-2007

Specialized Academic Board

Д 58.601.01

I. Horbachevsky Ternopil State Medical University

Essay

Dissertation is dedicated to investigation of correlations between functional status of vegetative nervous system and patterns of affection of small intestine by death-cup toxins. Conductive experimental studies have shown morphological peculiarities of small intestine's structures remodelling of depending on vegetative homeostasis of rats and under death-cup poisoning. Poisoning of experimental animals by death-cup toxins causes significant destructive, infiltrative processes of small intestine wall, marked vascular damage and substantial changes of local immune defence of mucous membrane. They are the most significant in jejunum and depend on duration of toxic action and features of vegetative homeostasis. It was broadened and supplied pathogenetycal mechanisms of investigated pathology considered vegetative organism’s homeostasis.

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