Asanov E. Age peculiarities of the reaction of human organism to hypoxic stress: mechanisms and ways of increasing of tolerance to hypoxia

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0508U000223

Applicant for

Specialization

  • 14.03.03 - Нормальна фізіологія

10-04-2008

Specialized Academic Board

Д 26.551.01

Essay

Object:ventilation,hemodynamics,exchange of gases,O2 transportation function of blood, microcirculation,tissue respiration,sympathoadrenal system,HRV,pro-antioxidant system,HIF in people different age.The purpose of investigation is to reveal the mechanisms of decreasing of tolerance to hypoxia in elderly people and development of approaches of its increasing. Methods: clinical,laboratory,Instrumental.It is caused by the decrease of the ventilatory and hemodynamic response in elderly people. It leads to depression of tissue respiration.At hypoxia in elderly people,we observe the expressed reaction of sympathoadrenal system and the oxidative stress.The application of both hypoxic trainings, and trimetilgidrazinija propionate raises the tolerance to hypoxia in elderly people.

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