Olijnyk I. Regularities of prenatal morphogenesis and forming of the structure of the branchiogenic group of glands

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0508U000569

Thesis Registration Form

0508U000569.pdf

Applicant for

Specialization

  • 14.03.01 - Нормальна анатомія

31-10-2008

Specialized Academic Board

Д 58.601.01

I. Horbachevsky Ternopil State Medical University

Essay

The dissertation research deals with a study of the regularities of embryogenesis and the dynamics of forming topographo-anatomical interrelations of the branchiogenic group of glands. Specific characteristics of the topographo-anatomical interrelations of the thyroid, thymus and parathyroid glands with the adjacent organs and structures from the moment of their anlage and until birth, as well as the periods of their intensive and retarded growth have been established. Individual and age-related variability of the branchiogenic glands throughout the human prenatal period has been revealed. Critical periods of the development and morphologic preconditions of a possible onset of congenital malformations of the branchiogenic glands have been studied. The application of a complex of methods of histomorphologic studies, cyto-, hysto- and lectinohystochemistry, biometry with different kinds of the statistical analysis have defined the tissue nature of the epithelium of the branchiogenic glands as the ectodermal one. It has become possible to establish the location and to prove the effect of a consecutive redistribution of glycopolymers – the receptors of lectins in the cells, on their surface and in the extracellular tissue structures in the process of on organo-specific differentiation of the epithelial and mesenchymal primordial of the thyroid, thymus and parathyroid glands.

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