Ruban О. Scientific grounding of the composition and technology of antiallergic medicinal preparations on the base of the black current’s polysaccharides

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0509U000348

Thesis Registration Form

0509U000348.pdf

Applicant for

Specialization

  • 15.00.01 - Технологія ліків, організація фармацевтичної справи та судова фармація

12-06-2009

Specialized Academic Board

Д64.605.02

Essay

The works deals with scientific-methodological approach to medicinal forms creation on the base of polysaccharides of the black current with the use of methods of mathematical experiment planning, mathematical models and programme «Optimization» and «Reology» complex. General systemic model of optimal tablets composition determination, which was used during the glucoribine tablets development has been built first. A complex of theoretical and experimental investigations dealing with technological and physical-chemical properties of glucoribine study has been carried out, influence of excipients on technological parameters and indicators of glucoribine tablets quality have been studied. Composition and technology of glucoribine ointment has been developed. Quality indicators dependency, structural-mechanical properties of the basis upon the emulgators, hydrophilic non- aqueous solvents presence and technological production parameters have been established. Construction improvements of some kinds of equipment used in the technological tablets and ointment production process has been performed.

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Дисертація Рубан О.А--ДОДАТКИ.doc

Дисертація Рубан О.А--РАЗДIЛ 1.doc

Дисертація Рубан О.А--РАЗДIЛ 2.doc

Дисертація Рубан О.А--РОЗДІЛ 3.doc

Дисертація Рубан О.А--РОЗДІЛ 3.doc

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Дисертація Рубан О.А--РОЗДІЛ 6.doc

Дисертація Рубан О.А--Список джерел.doc

Дисертація Рубан О.А--Титул. Зміст.doc

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