Boiko D. Clinical and experimental substantiation of the differential correction of the inflammation and metabolism of the connective tissue under bronchoobstructive and interstitial pulmonary diseases

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0513U001220

Applicant for

Specialization

  • 14.01.27 - Пульмонологія

25-11-2013

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

Object of research - chronic obstructive pulmonary disease, sarcoidosis, idiopathic pulmonary fibrosis. The goal of research - in patients with chronic obstructive pulmonary disease, sarcoidosis, idiopathic pulmonary fibrosis increase the effectiveness of the treatment of diseases by application of drugs with anti-inflammatory and antifibrotic action based on the results of experimental study and the use of improved tactical approaches to a process for the management of patients in view of the morpho-functional parameters of lung and system values of pro- and anti-inflammatory cytokines. Scientific novelty - the first time on the basis of clinical and experimental study substantiated differentiated approaches for correction inflammation and exchange of connective tissue at interstitial and bronchoobstructive respiratory diseases. Results: solved the problem of increasing the effectiveness of the treatment of patients with interstitial and bronchoobstructive lung disease by differentiated use of drugs with anti-inflammatory and antifibrotic effects, confirmed the results by experimental study and the use of improved tactical approaches to a process for the management of patients in view of the morpho-functional characteristics of damaged tissue, and system values pro- and anti-inflammatory cytokines. Scope - medicine.

Files

Similar theses