Slabyy O. Peculiarities of the heart chambers and vascular bed remodeling with arterial hypertension in the pulmonary circulation at depending of blood supply varies, hemodynamical types and vegetative regulation of cardiac muscle

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0518U000231

Applicant for

Specialization

  • 14.03.01 - Нормальна анатомія

16-10-2018

Specialized Academic Board

Д 05.600.02

Essay

Dissertation is devoted to the study of the features remodeling of the heart chambers and vascular bad with arterial hypertension in the small circle of circulation of depending on the types of blood supply, hemodynamics and vegetative regulation of myocardium. It is set that right pulmonectomy leads to postresection pulmonary arterial hypertension, cor pulmonale, that is characterized by irregular, disproportionate hypertrophy and dilatation of his chambers, the relative volumes of stroma, damaged cardiomyocytes, stromal-cardiomyocytic relation grow in that, capillary-cardiomyocyte relations, Kernogan's index and reserve volumes of ventricles, diminish, the wall of arteries is thickened, narrowing of the lumen, substantially the Vogenvort's index and percent of the damaged endotheliocytes grows in the arterial bed of myocardium, secretory activity of myoendocrinocytes of atria changes. Variations of the expressed violations of structural homoeostasis is revealed on organ, tissue, cellular, ultrastructural levels of heart with prevailing of them in a right ventricle and right auricle depends on the types of blood supply, hemodynamics and vegetative regulation of cardiac muscle.

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