Korenkov O. The comparative analysis of the dynamics of the healing of the defect of long bone diaphysis of skeleton after the implantation into its cavities of calcium-phosphate osteoplastic materials.

The thesis is devoted to identification of the morphological characteristics and rating densitometric, morphometric and mechanical parameters of the dynamics of the regenerative process of experimental defect of the diaphysis of the long bones of the skeleton depending on its implantation into the cavity with a calcium phosphate osteoplastic materials, which differ in origin, composition, manufacturer and release form. The rating of the maximum speed of resorption of osteoplastic material and its replacement with bone regenerate is presented by the area with the implanted Coll-SHA-G-g, and then β-TCP-b with β-TCP-g, SHA-β-TCP-NMP-p and NHA-g. NHA-g provides a high and stable densitometric, mechanical properties of the area of the defect of compact bone tissue, with no significant signs of resorption, and all the other products contribute to the full restoration of the absolute optical density, microhardness and hardness of the bone for 4 months.