Hudz N. Theoretical and experimental justification of the composition, technology and research of the solutions for peritoneal dialysis containing glucose and sodium lactate

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0521U100113

Applicant for

Specialization

  • 15.00.01 - Технологія ліків, організація фармацевтичної справи та судова фармація

15-01-2021

Specialized Academic Board

Д 26.613.04

PL Shupyk National Medical Academy of Postgraduate Education

Essay

The thesis is dedicated to the methodological, theoretical and experimental justification and development of the composition and technology of peritoneal dialysis solutions (PDSs). This thesis describes the course of the composition development from the initial idea to final composition of the PDSs. The following experimental results on the characteristics of the PDSs composition and technology were obtained and generalized: the influence of hydrochloric acid on the solutions pH level before and after sterilization, content of chlorides and glucose degradation products (GDP) which absorb ultraviolet light; the impact of the sterilization modes on the pH level of solutions and GDP content.

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