Petrovska L. Theoretical and experimental justification of the use of modern detergents in the technology of medical and cosmetic products

The dissertation is devoted to theoretical and experimental complex research in order to study the bases with anionic, amphoteric and nonionic detergents and the development of modern foaming agents in accordance with the optimal range of pH values within the physiological norm of a human being: foaming agents for infants and feminine hygiene. For the first time, a scientific and methodological approach with stages of theoretical and applied and experimental research on the peculiarities of the choice of detergent / Co-detergent system and other excipients in a narrow range of pH values (5.5-6.5) and (3.5-4.5). The developed methodology is a consistent implementation of a set of physical and chemical and pharmacological and technological research to create foaming agents for infants and for feminine hygiene that meet modern requirements. For the first time, a complex of technological and physicochemical studies of bases with selected detergents of anionic and amphoteric character. List of ingredients and technologies are scientifically substantiated, critical parameters of technological processes of production and methods of standardization are determined. The stability of the developed agents for infants and for feminine hygiene has been confirmed. The types of primary packaging are determined, storage conditions and expiration dates of foaming agents are proved. The biological efficiency and safety of the developed foaming agents in certain pH intervals have been studied. These foaming agents have been tested in industrial conditions.