Ostrovs'ka G. Experimental foundation of antioxidants use in conditions of xenobiotic diethylditiocarbomate influence

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U000301

Thesis Registration Form

0400U000301.pdf

Applicant for

Specialization

  • 14.03.05 - Фармакологія

26-01-2000

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

Investigation of diethilditiocarbomate influence on the development of a syndrome of peroxidation in conditions of different antioxidant provision as well as the studiing of protector effect of preparations with antioxidant qualities. It was determined that in prolonged on the experimental animals diethilditiocarbomate caused the development of hyperlipidemia, the increase of the level of product of lipid peroxidate oxidation, the lowering of the provision on the rats' organism with hydrophiic antioxidants as well as sharp inhibition of superoxiddismutase, catalase and ceruloplasmin. It was recommended that the use of ceruloplasmin preparations, tocopherol-acetate, thiotriosolin, echinacea purpurea extract inhibited the development of a syndrome of peroxidation

Read more

Similar theses

0422U100029

Sheikhali Ali Marsel

Experimental justification for the use of a new combined cream "Dermalipoin" for the treatment of purulent-inflammatory skin diseases

0422U100006

Dub Anastasiia Ihorivna

Experimental approach of the antidiabetic activity of the new phytocomposition

0421U102934

Stefaniv Ivan Volodymyrovych

Pharmacological characteristics of the new herbal medicine «Kasdent» for the treatment of inflammatory diseases of periodontium and oral mucosa

0421U102041

Prokopchuk Elena Gennadyevna

Complex compounds of Sn (IV) with salicyloylhydrazones of benzaldehydes as potential biologically active substances with anti-inflammatory, analgesic and concomitant pharmacological action

0521U101312

Nosivets Dmitriy Sergeevich

Pharmacological analysis of analgesia and chondroprotection in experimental osteoarthritis on the background of hypothyroidism