Antonenko P. Neurotropic effects of new biologically active substances - co-ordinating compounds of germanium with bioligands.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U000319

Thesis Registration Form

0400U000319.pdf

Applicant for

Specialization

  • 14.03.05 - Фармакологія

24-01-2000

Specialized Academic Board

Д 41.600.01

Odessa National Medical University

Essay

Neurotropic activity of a newly synthesized co-ordinating compounds of germanium and bioligands, such as nicotinic and amber acid (correspondently MIGU-1 and 3) as well as nicotinamid (MIGU-2) has been carried out. At correspondent models it was established that according to the spectrum of neurotropic activity MIGU-1,2,3 may be attributed to tranquillizers. MIGU-2,3 compounds reveal the properties of nootrops, they also effective during electroconvulsive shock as well as are capable of potentiating the activity of standard anticonvulsants during experimental seizures, that open's perspective the purpose investigation of them.

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