Legen'kyj V. The effects of NO and its donors on contractility and intracellular calcium level of arterial smooth muscles

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U002805

Thesis Registration Form

0401U002805.pdf

Applicant for

Specialization

  • 14.03.05 - Фармакологія

23-10-2001

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

NO relaxes arterial smooth muscles of rat tail artery not only due to decrease in intracellular calcium level, but also due to decrease in calcium-sensitivity of regulating and/or contractile proteins. The ability to relax arterial smooth muscles and decrease in intracellular calcium level via a cGMP-independent way is intrinsic for all the studied compound.

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