Kvitchata G. Vestibuloprotectors activity and the mechanism of action of bemithyl and etoxibemithyl.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U003378

Applicant for

Specialization

  • 14.03.05 - Фармакологія

05-12-2001

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

Comparative analysis of vestibuloprotective activity Mercaptobenzimidazol derivates in case of experimental motion sickness wos carried out. It is proved bemityl and etoxibemithyl intraperitoneal single 100 and 200 mg/kg supresses influence of duration amplitude and frequene rotationof vestibular nystagmus. The studied substance are very effective by cAMF in adrenal glands, midbrain and cerebral cortex. The intensification of RNA is the mechanism o action bemithyland etoxibemithyl in case motion sickness.

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