Vrynchanu N. Antiviral activity of new derivatives of adamantane and norbornane.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U001062

Applicant for

Specialization

  • 14.03.05 - Фармакологія

20-03-2002

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

The dissertation is devoted to searching compounds with antiviral activity among new derivatives of adamantane and norbornane. It has been shown that AB-4 inhibits viral specific DNA-polymerase , timidinekinase and induces interferone synthesis. By its antiviral activity and interferonogenic effect AB-4 overcomes remantadine and acyclovire. AB-32 also performs interferonogenic, antibacterial and antifungal properties.

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