Kurapova T. Pharmacological correction by derivatives of pyridinecarboxylic acids of the peroxide modification of membrane hepatocytes under tetrachloromethane intoxication

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U001178

Applicant for

Specialization

  • 14.03.05 - Фармакологія

16-02-2005

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

The dissertation is dedicated to the research on the effects of derivatives of pyridinecarboxylic acids on the state of lipid peroxidation and structural-dynamic parameters of endoplasmic reticulum membranes of the liver cells under tetrachloromethane intoxication. The application of substances PV-4 and Amizon under tetrachloromethane intoxication resulted in the correction of the structural-dynamic parameters of endoplasmic reticulum membranes of the rat liver cells and the essential normalization of blood serum antioxidative properties.

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