Dychakovska O. Study of the role of sexual hormones in the development of morphine withdrawal syndrome.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U001294

Applicant for

Specialization

  • 14.03.05 - Фармакологія

16-03-2005

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

The dissertation is devoted to the analysis of influence of sexual hormones on creation of depend-ence on Morphine, which valued both on current withdrawal syndrome, and on timing development of a tolerance to the Morphine analgetic effect. Results of this study testify that Testosterone treatment strengthens an expressiveness of the withdrawal syndrome and accelerates formation of a tolerance to Morphine analgetic effect, whereas the Testosterone receptor blockers, surgical and chemical castration have opposite effect on researched processes.

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