Mykhalska V. The clinical condition and metabolic status of chickens-broilers at using complex compound of cooper

The object - metionat, glycinat, and lysinat of copper, rat and mouse of laboratory, chickens-broilers. The aim - to perfect the method of synthesis, explore toxic properties and to study influence of metionat, glycinat, and lysinat of copper on the clinical state, metabolic status and productivity of chickens-broilers The methods - clinical, hematological, hygiene, stock-breeding, biochemical and statistical methods of results processing. The novelty - in theory grounded and experimental possibility of the use of complex compounds is well-proven are metionat, glycinat, and lysinat of copper in feeding of laboratory animals and chickens-broilers. Complex compounds of copper with methionine, glycine and lysine after the degree of unsafely are the low toxic substances: LD50 of which for mice is accordingly 335,0; 640,0 and 390,0 mg/kg the masses of body. The increase stimulant influencing of glycinat, and lysinat and less measure metionat of, copper is set, on activity of digestive enzymes of chickens-broilers of in vitro. At introduction to the rats of metionat, glycinat, and lysinat of copper increase formation of energy in fabrics of organism in different quantities, the processes of ureogenesis went down in a liver, activity of digestive and tissues enzymes changed and the albuminous spectrum of whey did not change bloods, hematological indexes and clinical state of animals. The research results were included to the metodical recommendations "The introduction complex compounds of copper and zinc in feeding chickens-broilers", which have been proved by the State Department of Veterinary Medicine of Ministry of agrarian policy of Ukraine (registered №43, 06.05.2005 year). The branch - veterinary medicine.