Stopinchuk O. The increase of pharmacotherapy efficacy of metoprolol in ischemic heart disease by its joint using with thiotriasoline or mebicar

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U005137

Applicant for

Specialization

  • 14.01.28 - Клінічна фармакологія

20-12-2006

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

The dissertation is devoted to studying of influence of complex therapy with metoprolol and thiotriasoline or mebicar on clinical course, haemodynamic parameters, lipids of blood, manifestation of psychical depression and life quality of the patients with ischemic heart disease (stable angina pectoris II - III functional class). For the first time, in clinical conditions there was shown greater clinical efficacy of metoprolol with thiоtriasoline and metoprolol with mebicar versus metoprolol. Comparative analysis of pharmacotherapy with metoprolol and thiotriasoline versus metoprolol and mebicar was performed for the first time.

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