Chaus T. Bioelectric activity of rats' hypothalamus in con-ditions of stress and modulation of synaptic transmission with psychopharmaceuticals

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U003554

Applicant for

Specialization

  • 03.00.13 - Фізіологія людини і тварин

19-09-2007

Specialized Academic Board

Д 26.001.38

Taras Shevchenko National University of Kyiv

Essay

The regularities of dynamics of bioelectric activity of rats' dorsal and anterior areas were investigated. We showed that the prepotent rhythm in defined areas of animals under examina-tion was delta-like activity. We determined that in physiological conditions absolute measures of capacity of all researched rhythms were larger in anterior hypothalamic area. Although rela-tive measures in both hypothalamic areas were almost the same. We found out that in condi-tions of zoo conflict situation absolute and relative measures of the major hypotalamogram rhythms were almost always lower than the measures of the animals from a control group. Relative measures of hypotalamogram rhythm capacity of the animals which we gave amitrip-tylinum on the back of the stress were lower than measures of animals that lived in stress condi-tions. In conditions of reserpine usage only absolute measures of hypotalamogram capacity were larger than figures of the rats that were under the stress. Besides, these figures were larger in anterior hypothalamic area. Against gidazepamum usage only in anterior area we could see the decrease of relative measures of major hypotalamogram rhythms capacity towards the ani-mals that lived under the stress. Although those measures in dorsal area were larger in compari-son with anterior area. Key words: anterior hypothalamic area, dorsal hypothalamic area, zooconflict stress, bio-electric cerebrum activity, amitriptylinum, reserpine, gidazepamum.

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