Dmytriieva K. Biochemical mechanisms of xenobiotic-matabolising enzymes demage's of a liver in cosequence of the burn trauma of skin and its correction by antioxidants- trimetazidine and mexidol.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U004429

Thesis Registration Form

0407U004429.pdf

Applicant for

Specialization

  • 14.01.32 - Медична біохімія

01-11-2007

Specialized Academic Board

Д. 26.003.07

Essay

The dissertation is devoted to the investigation of biochemical mechanisms the influence of the burn damage of skin on the system of xenobiotic biotransformation and the ground of expediency to use the drugs with antioxidant activity to protections metabolising enzymes systems. The inhibition of enzymatic activity in oxidative and conjugated stages of xenobiotic metabolism, the delay of drug elimination from organism, the increase its pharmacological activity, dependent on severity of injury, were recognized. Trimetazidine surpassed mexidol both on the intensity of membraneprotective actions, and on the ability to protect systems of xenobiotic's biotransformation under burn damages.

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dis-Висновки.doc

dis-Вступ.doc

dis-Розділ 1.doc

dis-Розділ 2.doc

dis-Розділ 3.doc

dis-Розділ 4.doc

dis-Розділ 5.doc

dis-Розділ 6.doc

dis-Титул.doc

dis-список літератури.doc

автореферат-aref-titul.doc

автореферат-aref.doc

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