Androsova M. The role of opioids in apoptosis mechanisms regulation in experiment of acute heart failure

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U003618

Applicant for

Specialization

  • 14.01.32 - Медична біохімія

12-06-2008

Specialized Academic Board

Д 29.600.03

Essay

The dissertation is dedicated to studying of a biochemical regulation of apoptosis on heart insufficiency formation in signal pathways of cell processes regulation - opioid receptors, sphingomyelinal, nitrogen monoxide and in cell volume regulation. It was established what cell death program stimulation on experimental acute heart failure is accompanied with decreasing of antioxidant properties of organism, sphingomyelin pathway activation, also increasing on nitrogen monoxide stable metabolites level, with overhydration of cardiomyocyte

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