Mashevska O. Role of the processes of metabolic activation and oxidative stress in the mechanisms of xenobiotic-induced nephrotoxicity.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U000946

Applicant for

Specialization

  • 14.01.32 - Медична біохімія

17-03-2011

Specialized Academic Board

Д 29.600.03

Essay

Dissertation is devoted to the studying the role of oxidative stress, processes of mobilization of iron and metabolic activation in realization of nephrotoxic effect of cisplatin, glycerol and brombenzol and establishment the pathogenetic ways for prophylactic of their nephrotoxicity by use of xenobiotic metabolizing enzyme inhibitors, antioxidants and iron chelating agent.

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