Novosad A. Effect of melatonin on rhythms of sleep and blood pressure in a combined drug therapy of hypertension

The dissertation is dedicated the investigation problems diagnosing sleep disorders in different age groups and pharmacotherapy of insomnia by melatonin in patients with hypertension. For the first time a comparison of quantitative and qualitative characteristics of insomnia two contingent on age (in young individuals of the control group) and in patients with essential hypertension. The structure of sleep disorders in young persons have not been studied. It is shown that in the context of antihypertensive therapy hypertension basic in-patient treatment of sleep quality characteristics deteriorate. The effectiveness of melatonin as a regulator of circadian rhythms BP increased with age of patients was more peculiar to women and patients with symptoms of excess body weight. Melatonin pharmacotherapy for two weeks was insufficient for positive dynamics was achieved through the month, this time side effects of melatonin were observed.