Ivanova E. Medical and prophylactic effectiveneess of vinboron of doxorubicine cardiomyopathy

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U002570

Applicant for

Specialization

  • 14.03.05 - Фармакологія

18-04-2013

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

The dissertation is devoted to improving the effectiveness and safety of treatment of anthracycline antibiotics based on a study of the drug with cardioprotective properties - vinboron. In animal experiments it was proved that during the medical introductions of vinboron during acute and chronic myocardial doxorubicin damage the drug demonstrates a pronounced cardioprotective effect. By the magnitude of cardioprotective action in experimental acute doxorubicin myocardiodystrophy vinboron almost matched against thyotriazoline and sometimes dominates the latter, especially in experimental chronic doxorubicin cardiomyopathy.

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