Egorov A. Experimental justification of L-lysine formations using in the conditions of acute cerebral circulation disorders

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0414U001583

Thesis Registration Form

0414U001583.pdf

Applicant for

Egorov Artyom Anatoliyvych

Specialization

14.03.05 - Фармакологія

Date of defense

02-04-2014

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

Dissertation work is devoted to the study of the neuroprotective properties of compounds of L-lysine in the conditions of experimental modeling of acute cerebral circulation disorders. Introduction compounds of L-lysine in the dose of 50 mg/kg in the conditions of acute cerebral circulation disorders demonstrated the decrease in the mortality of animals in the experimental groups and reduction of neurological deficit. As a result of pharmacological and biochemical studies, we have identified the most active compound L-lysine - "Lysinii". Conducting morphometric studies showed high neuro - and endoteliotrope activity.

Thesis supervisor

Belenichev Igor

Official opponents

Французова Стелла Борисівна
Горчакова Надія Олександрівна

Files

aref.doc

dis.doc

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