Krajewski S. Effect of different types of suture material on the wound process and its correction with cord blood serum in animals

Object of research - dogs and cattle with postoperative wounds. A research objective - to study the effect of different types of suture material on the course of wound healing and substantiation of its correction with cord blood serum in animals. Research methods: clinical, strain gauges (physical and mechanical properties of suture materials - tensile strength and knot), total blood count (red blood cells, white blood cells, hemoglobin, erythrocyte sedimentation rate), biochemical (glycoproteins, glycosaminoglycans, glycoproteins hlororozchynni, seromucoid, ceruloplasmin, sialic acid ), histological and statistical. Scientific novelty: There were studied the spreading of postoperative complications in dogs after the imposition of submersible seams of natural and synthetic fibers. Capron and prolen do not lose the whole strength and ligatures in node after insertion into the subcutaneous tissue or muscle tissue in dogs and cattle for 90 days. Vicryl and polydioxanone more quickly lose strength when inserted into the subcutaneous tissue and muscle tissue in dogs compared with calves. Vicryl and nylon used for the purpose of suturing the incision in dogs and calves cause minimal local inflammatory reaction compared with catgut and silk. This indicates their high biological and chemical inertness. Dynamics of markers of connective tissue of animals indicates the maximum manifestation of inflammatory response to the 4th day after the operation under the influence of cord blood serum, which further helped to accelerate the healing of surgical wounds by 1.3-2.4 days. Implementation: materials are used in the classroom while teaching "Veterinary Surgery" and in research (Bilotserkivskiy National Agrarian University, Sumy National Agrarian University, Zhytomyr National Agroecological University, Lugansk National Agrarian University, Podolsky State Agrarian Technical University). Sphere (branch) of use: veterinary medicine